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第五步——浸润性癌，如果基因变化使肿瘤开始侵入下层组织，并使细胞脱落到血液或淋巴中， 则认为肿瘤已变成恶性肿瘤。癌变的细胞很可能在全身形成新的肿瘤（转移）；这些可能会因破坏重要器官而致命。
腫瘤在其生長過程中，雖然能夠暫時通過建立新生血管解決自身給養問題，但是快速的增長一樣會將之推向資源和空間匱乏的邊緣。隨著腫瘤細胞持續生長，在這樣競爭的壓力下，這時腫瘤就會擴散。而這種腫瘤在生長過程中侵略性不斷增加的過程則被稱為演進（development）。具體的行為則是生長的加快，並且開始入侵周遭的正常組織（癌症浸潤），並且通過血管轉移到遠端（癌症轉移）。
用醫學影像技術檢測癌症，也遭遇類似問題。這些醫學影像檢測技術都是成本相當高且耗費時間。由於偵測的靈敏度極高，常發現細胞病變（英语：incidentaloma），這樣的腫瘤也可以被認為惡性，而進行具有潛在危險性的治療方法。
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癌症扩散。随着癌症进展，它可能扩散（转移）到身体其他部位。癌症扩散到哪里取决于所患癌症的类型。
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一些最常见的癌症类型，如乳腺癌、宫颈癌、口腔癌和结肠直肠癌等，如能早期发现并根据最佳做法进行治疗，治愈概率很高。
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Activating the Highly developed AI mode is not hard: slide around the toggle switch while in the higher correct corner with the chat window. Our subscription offers a pack of advanced messages, as well as the concept counter beside the toggle swap displays the exact amount of money you have still left.
减少接触室外和室内空气污染，包括氡（一种由铀的自然衰变产生的放射性气体，可能在建筑物中，住宅、学校和工作场所积累）。
Other search engines affiliate your advert-click conduct which has a profile on you, that may 癌症 be used afterwards to focus on adverts to you personally on that online search engine or all-around the online market place.
癌症复发。癌症幸存者有癌症复发的风险。有些癌症比其他癌症更容易复发。请咨询医生如何降低癌症复发的风险。治疗后，医生可能会为您设计一份随访护理计划。该计划可能包括在治疗后的几个月和几年里定期进行扫描和检查，以寻找癌症复发的迹象。